CME: Identification and management moderate-to-severe psoriatic arthritis: stopping the disease in its tracks and meeting unmet needs (NON-ACCREDITED)
Activity Description / Statement of Need:
Psoriatic arthritis (PsA) is a chronic, progressive disease that, untreated, may be associated with permanent joint damage, disability, impaired quality of life, and cardiovascular disease. Globally, it affects 0.1-1% of people, it is a common comorbidity of patients with psoriasis, affecting up to a quarter of those with moderate-to-severe disease. affecting them in a quarter percent of the U.S. population. PsA is an immune-mediated disease characterized by inflammation of the skin and nails disease or a family history of psoriasis in association with pluralistic musculoskeletal disease that may involve entheses, the spine, and peripheral joints. Unlike the clinical manifestations of inflammatory, pathophysiological processes of psoriasis, a failure to intervene early in PsA with treatment often results in damage that is irreversible. In all, patients with PsA incur about four times the direct medical costs as compared to the average medical patient.
This accredited educational activity identifies the critical components of the management process and offer solutions to close gaps in diagnosis and care, with the ultimate goals being the improvement of psoriatic arthritis management, treatment adherence, and health and cost outcomes.
Target Audience:
The following HCPs: rheumatologists, dermatologists, and primary care physicians; physician assistants, nurse practitioners, and pharmacists who practice in rheumatology and immunology; and any other HCPs with an interest in or who clinically encounter patients with PsA.
This program is supported by an educational grant from Mylan Inc., a Viatris Company.
This activity is free of charge.
Release Date: May 15, 2022 -- Expiration Date: May 15, 2024
Faculty: Peng Fan, MD
Agenda
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Faculty introduction, |
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Introduction content: cursory refresher and review of PsA Epidemiology: statistics by severity Pathophysiology Clinical presentation; disease progression; complications, comorbidities, and burden of disease Evaluation, diagnosis, and associated pitfalls |
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Treatment of PsA Peripheral arthritis vs. axial disease Prognosis Moderate-to-severe disease treatment cDMARDs: methotrexate, leflunomide, and phosphodiesterase-4 inhibition Adverse prognosis and resistance to cDMARDs Tumor necrosis factor-targeting therapy IL-17, -12, and -23-targeting therapies Selective T-cell costimulation Janus kinase inhibition Later-line agents Monitoring Recent clinical trial evidence and guideline updates Emerging and future therapies Disease flares and adverse events Patient case(s) |
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Summary, conclusions, and best practice recap |
Learning Objectives
By the end of the session the participant will be able to:
- Recall barriers to optimal care in patients with PsA, including the burden of disease, consequences of delayed diagnosis, and suboptimal therapy
- Describe guideline-recommended and investigational pharmacotherapy for moderate-to-severe PsA
- Formulate a treatment plan for a patient with moderate-to-severe PsA
Accreditation
This activity is not accredited.
Faculty Disclosure and Resolution of COI
Faculty: Peng Fan M.D. FACP, Clinical Professor of Medicine, Division of Rheumatology,David Geffen School of Medicine at UCLA, has received financial compensation from Amgen, Pfizer, Abbvie, Sanofi, Novartis, Radius, and Regeneron for speaker's bureau work.
Faculty WILL discuss off-label use of a commercial product.
Disclosures of Educational Planners: Charles Turck, PharmD, BCPS, BCCCP, CEO of ScientiaCME, has no relevant financial disclosures.
Commercial Support Disclosure: This program is supported by an educational grant from Mylan Inc., a Viatris Company.
Instructions
- Read the learning objectives above
- View the online activity. You may view this is in more than one session, and may pause or repeat any portion of the presentation if you need to.
System Requirements
Windows 7 or above
Internet Explorer 8
*Adobe Acrobat Reader
Mac OS 10.2.8
Safari or Chrome or Firefox
*Adobe Acrobat Reader
Internet Explorer is not supported on the Macintosh
*Required to view Printable PDF Version
Please take a few minutes to participate in the optional pre-test. It will help us measure the knowledge gained by participating in this activity.