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CME: Saving lives: New paradigms of care for opioid use disorder (OUD)


Activity Description / Statement of Need:

In this online CME self-learning program: Opioid use disorder (OUD) affects millions of individuals globally and is best defined by the DSM-5 as a condition due to tolerance, manifestation of physical dependence, and loss of control, which in turn leads to health hazards. The prevalence of OUD and the resultant impact on people is staggering, an estimated 130 people die from opioid overdoses every day. Moreover, the prevalence of OUD is increasing rapidly in concurrence with the widespread availability of opioids, with an estimated 60 prescriptions per 100 patients.

Professional societies, non-governmental organizations, and governmental agencies have all recommended a comprehensive public health approach to identifying and managing OUD, which will require the involvement of HCPs across specialties and regions. Implementing a comprehensive multidisciplinary cascade of care for patients with OUD will also necessitate that HCPs embrace new resources to deliver innovative and accessible health care. These resources may include novel prescription digital therapeutics, telemedicine, and engagement of non-physician HCPs who can provide support, counseling, and, in some cases, prescribing.

Target Audience:

Healthcare professionals specializing in: Addiction, pain management, primary care, family medicine, psychiatry; physician assistants, nurse practitioners, nurses, and pharmacists who practice in pain management or substance abuse; and any other health professionals who encounter OUD in the clinical setting.

This program is supported by educational grants from Indivior and The Modami Foundation.

Learners may participate in this activity free of charge.

Release Date: March 20, 2021 -- Expiration Date: March 20, 2023

Faculty: Michael Levine, MD


Faculty introduction, disclosures

Epidemiology of OUD

  • OUD trends
    • Increasing incidence
    • Concordance with opioid prescribing
  • Impact on patients and society
    • Morbidity and mortality
    • Cost
    • Health care resource use

Treatment of OUD

  • Therapeutic modalities
    • Cognitive behavioral therapy
    • Counseling
    • Pharmacotherapy
    • Prescription digital therapeutics
  • Medication-assisted treatment options
    • Methadone
    • Buprenorphine/naloxone
    • Naltrexone
    • Available formulations (e.g., oral, implant, injections)
  • Opioid detoxification and withdrawal
  • Individualizing treatments
    • Adult vs pediatric perspectives
    • Pregnancy
    • Incarceration
    • Patients suffering from acute or chronic pain
    • Intensive care unit and emergency departments
  • Best practices
    • Implementation and selection of treatment
    • Engaging multidisciplinary team
    • Improving access through novel technology
  • Patient case(s)

Summary, conclusions, and best practice recap

Learning Objectives

By the end of the session the participant will be able to:

  • Describe the changing trends in OUD and the emerging roles for clinicians across specialties in identifying and managing OUD.
  • Evaluate recent efficacy and safety data for novel formulations of medication-assisted treatments for OUD, select patients who would benefit from long-acting formulations based on patient cases.
  • Identify challenges associated with the selection and implementation of drug regimens to the treatment of OUD and dependence, including risk factors for opioid overdose.
  • Develop strategies for recognizing and improving therapeutic adherence in patients treated for OUD and opioid dependence.


ACCME Activity #201718496


Faculty Disclosure and Resolution of COI

As a provider of continuing medical education, it is the policy of ScientiaCME to ensure balance, independence, objectivity, and scientific rigor in all of its educational activities. In accordance with this policy, faculty and educational planners must disclose any significant relationships with commercial interests whose products or devices may be mentioned in faculty presentations, and any relationships with the commercial supporter of the activity. The intent of this disclosure is to provide the intended audience with information on which they can make their own judgments. Additionally, in the event a conflict of interest (COI) does exist, it is the policy of ScientiaCME to ensure that the COI is resolved in order to ensure the integrity of the CME activity. For this CME activity, any COI has been resolved thru content review ScientiaCME.

Faculty Disclosure: Michael Levine, MD, Department of Emergency Medicine, University of California, Los Angeles, has no relevant conflicts of interest to disclose.

Disclosures of Educational Planners: Charles Turck, PharmD, BCPS, BCCCP, President of ScientiaCME, has no relevant conflicts of interest to disclose. 

Commercial Support Disclosure: This program is supported by educational grants from Indivior and The Modami Foundation.


  • Read the learning objectives above
  • Take the Pre-Test (optional). Completion of the pre-test will help us evaluate the knowledge gained by participating in this CME activity.
  • View the online activity. You may view this is in more than one session, and may pause or repeat any portion of the presentation if you need to.
  • Minimum participation threshold: Take the post-test. A score of 70% or higher is required to pass and proceed to the activity evaluation.
  • Complete the activity evaluation and CME registration. A CE certificate will be emailed to you immediately.

Cultural/Linguistic Competence & Health Disparities

System Requirements

Windows 7 or above
Internet Explorer 8
*Adobe Acrobat Reader
Mac OS 10.2.8
Safari or Chrome or Firefox
*Adobe Acrobat Reader
Internet Explorer is not supported on the Macintosh

*Required to view Printable PDF Version

Perform Pre-Test (optional)

Please take a few minutes to participate in the optional pre-test. It will help us measure the knowledge gained by participating in this activity.

Additional Courses That Are Related To This Activity

Opioid dependence and opioid use disorder: Best practices, barriers in care, and the role of long-acting injectable medication

Updates in alcohol use disorder (AUD) pharmacotherapy and barriers to optimal care

Bipolar and mood disorder: Therapeutic updates and best practices

Addressing barriers to optimal care in schizophrenia with pharmacotherapy