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CME: 5th Right Heart Symposium: Part 3


Activity Description / Statement of Need:

***Please note that, in order to access these course materials, you must create a user profile if you do not already have one. Your profile one ScientiaCME's website is unrelated to your profile on North American Thrombosis Forum's (NATF's) website.***

The content of this online activity was presented originally at a live event. It is divided into three videos. Learners must view both videos in their entirety and complete a post-activity assessment and evaluation before they are eligible for continuing credit.

The North American Thrombosis Forum's (NATF’s) “5th Right Heart Symposium”

The syndrome of right heart failure is poorly understood and defined. Clinicians often fail to diagnose early stages of the disease and allow the manifestations to progress to severe disability. There is a pressing need to define, understand, and inculcate awareness about this disease in clinicians. Similarly, understanding right heart dysfunction requires focused investigations and research study, best brought forth by a multidisciplinary collaboration. This program is intended for clinical and research professionals who are involved in the care of patients with, and the study of, right heart disease, congenital heart disease, pulmonary hypertension, and associated disorders.

Target Audience:

Target audience:

• Physicians
• Pharmacists
• Hospitalists
• Surgeons
• Nurses
• Nurse practitioners
• Physician assistants
• Allied healthcare professionals

In the following fields:
– Cardiology
– Pulmonology
– Critical care medicine
– Emergency medicine
– Rheumatology
– Internal medicine
– Vascular medicine

Supported by educational grants from: Abbott Laboratories; Acceleron Pharma Inc.; Actelion Pharmaceuticals US, Inc., a Janssen Pharmaceutical Company of Johnson & Johnson; and United Therapeutics.

This internet enduring material activity is part of a series of activities. Participation in this activity is free of charge.

Release Date: May 04, 2022 -- Expiration Date: May 03, 2023

Faculty: Multiple Faculty,


Pulmonary Heart Disease and Remodeling


  • Bradley A. Maron, MD, Associate Physician, Brigham and Women's Hospital
    Associate Professor of Medicine, Harvard Medical School
  • Dr. Eileen Harder, MD, is a internal medicine specialist in Boston, MA. She currently practices at Brigham & Womens Hosp Emergency


How Does Pulmonary Disease Drive Pulmonary Vascular and Myocardial Remodeling? – Paul Hassoun, MD, Professor of Medicine, Johns Hopkins University; Director, Pulmonary Hypertension, Program Johns Hopkins Hospital

How Does Left Heart Disease Drive Pulmonary Vascular and Right Ventricular Remodeling? – Stephan Rosenkranz, MD, Professor, University of Cologne; Doctor, University of Cologne Heart Center

How Does Congenital Heart Disease Drive Pulmonary Vascular Remodeling? – Mary Mullen, MD, PhD, Assistant Professor in Pediatrics, Harvard Medical School; Associate in Cardiology, Boston Children’s Hospital

Right Heart Disease in the Absence of Pulmonary or Left Heart Disease – Michael Givertz, MD, Professor of Medicine, Harvard Medical School

Molecular Phenotyping of the Right Heart System: Is the Fog Starting to Clear? – Jane Leopold, MD, FACC, FAHA, FSCAI, Associate Professor of Medicine, Harvard Medical School; Director
Women’s Interventional Cardiology Health Initiative, Brigham and Women’s Hospital

Panel Discussion


Interventional Approaches to the Failing Right Heart

ECMO as a Bridge – Paul M. Heerdt, MD, PhD, Professor of Anesthesiology & Director of Applied Hemodynamics, Yale New Haven Hospital and Yale School of Medicine

Chromic Thromboembolic Pulmonary Hypertension: Surgical, Medical, and Interventional Options for Treatment – Piotr Sobieszczyk, MD, Instructor of Medicine, Harvard Medical School; Associate Physician, Brigham and Women’s Hospital

Percutaneous Approaches to RV Support Now and in the Future – Steven P. Keller, MD, Assistant Professor of Medicine and Biomedical Engineering, Johns Hopkins University

Panel Discussion

Learning Objectives

By the end of the session the participant will be able to:

  • Discuss the importance of RV and pulmonary arterial coupling and its role in RV function and RV failure
  • Evaluate the current data regarding myocardial metabolism and RV function
  • Describe RV adaptation and maladaptation in pulmonary arterial hypertension (PAH) and the effectiveness and adequacy of current therapies used in management of PAH
  • Given a patient case, formulate a management approach that takes into account RV structure, function, and maladaptation


ACCME Activity #202288293


Faculty Disclosure and Resolution of COI

  • Moderator: Bradley A. Maron, MD: Steering Committee Member – Actelion; Investigator –Sponsored Research, Deerfield Corporation
  • Paul Hassoun, MD: Paid Consultant – MS&D
  • Paul M. Heerdt, MD, PhD: Paid consultant – Philips, BaudaxBio, Baxter
  • Steven Keller, MD: Paid Consultant – Abiomed, Inc., X-COR Therapeutics, Inc., CBSET, Inc.; Advisor – Paragonix Technologies
  • Jane A Leopold, MD: Research Funding – Aria CV, Astellas, Inc.; Consultant –Abbott Vascular; Speaker – United Therapeutics
  • Stephan Rosenkranz, MD: Paid Consultant – Abbott, Acceleron, Actelion, Bayer, Janssen, MSD, Novartis, United Therapeutics, Vifor; Research Grants – Actelion, AstraZeneca, Bayer, Novartis, Janssen; Speaker – Actelion, Bayer, BMS, Ferrer, Janssen, MSD, Novartis, Pfizer, United Therapeutics, Vifor

Individuals with no conflicts of interest to disclose:

  • Content reviewer: Charles J Turck, PharmD, BCPS, BCCCP, President, ScientiaCME
  • Moderator: Eileen Harder, MD
  • Michael Givertz, MD
  • Mary P. Mullen, MD, PhD
  • Piotr Sobieszczyk, MD


  • Read the learning objectives above
  • Take the Pre-Test (optional). Completion of the pre-test will help us evaluate the knowledge gained by participating in this CME activity.
  • View the online activity. You may view this is in more than one session, and may pause or repeat any portion of the presentation if you need to.
  • Minimum participation threshold: Take the post-test. A score of 70% or higher is required to pass and proceed to the activity evaluation.
  • Complete the activity evaluation and CME registration. A CE certificate will be emailed to you immediately.

Cultural/Linguistic Competence & Health Disparities

System Requirements

Windows 7 or above
Internet Explorer 8
*Adobe Acrobat Reader
Mac OS 10.2.8
Safari or Chrome or Firefox
*Adobe Acrobat Reader
Internet Explorer is not supported on the Macintosh

*Required to view Printable PDF Version

Perform Pre-Test (optional)

Please take a few minutes to participate in the optional pre-test. It will help us measure the knowledge gained by participating in this activity.