In this online, self-learning activity:
Over a quarter million women and almost 2,700 men in the U.S. are diagnosed with breast cancer each year, and it is the second leading cause of cancer death in women. The prognosis associated with breast has improved in the last few decades due in larger part to earlier detection. Detection at the loco-regional stage is associated with a five-year overall survival (OS) rate of ≥ 85% in contrast to 27% for distant or metastatic breast cancer (mBC).
This activity has been designed to bring healthcare professionals’ knowledge of the rationale behind treatment of mTNBC up to date and to improve their competence and performance in treating it.
The following HCPs: medical oncologists; physician assistants, nurse practitioners, and pharmacists who practice in oncology; and any other healthcare professionals with an interest in or who clinically encounter patients with breast cancer.
Commercial Support Disclosure: This program is supported by an educational grant from Merck.
This activity is free of charge.
Release Date: October 27, 2021 -- Expiration Date: October 27, 2022
Faculty: Yuan Yuan, MD, PhD
Faculty introduction, disclosures
Introduction content: cursory refresher and review of mTNBC
· Presence vs. absence of rapidly progressive visceral disease
· ± BRCA mutation, ± progression on a PARP inhibitor
· ± PD-L1
· Previous chemotherapy exposure
· Microsatellite instability-high / mismatch repair-deficient tumors
· Later-line therapies
· Emerging therapies
· PARP inhibitors
· PI3K / AKT
· Adverse effect identification and management
· Gaps in care
Summary, conclusions, and best practice recap
By the end of the session the participant will be able to:
ACCME Activity #201761696ACCREDITATION FOR THIS COURSE HAS EXPIRED. YOU MAY VIEW THE PROGRAM, BUT CME / CE IS NO LONGER AVAILABLE AND NO CERTIFICATE WILL BE ISSUED.
As a provider of continuing medical education, it is the policy of ScientiaCME to ensure balance, independence, objectivity, and scientific rigor in all of its educational activities. In accordance with this policy, faculty and educational planners must disclose any significant relationships with commercial interests whose products or devices may be mentioned in faculty presentations, and any relationships with the commercial supporter of the activity. The intent of this disclosure is to provide the intended audience with information on which they can make their own judgments. Additionally, in the event a conflict of interest (COI) does exist, it is the policy of ScientiaCME to ensure that the COI is resolved in order to ensure the integrity of the CME activity. For this CME activity, any COI has been resolved thru content review ScientiaCME.
Yuan Yuan, M.D., Ph.D., Associate Clinical Professor, Department of Medical Oncology and Therapeutic Research, City of Hope Comprehensive Cancer Center, has received financial compensation for research and/or consulting from : Pfizer, Merck, Genentech, Eisai, Novartis, Immunomedics, Gilead, Imugene, and AstraZenica.
Disclosures of Educational Planners: Charles Turck, PharmD, BCPS, BCCCP, President of ScientiaCME, has no relevant financial disclosures.
Faculty will not discuss off-label uses.
All relevant financial relationships have been mitigated.
ScientiaCME adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers or others are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.
Commercial Support Disclosure: This program is supported by educational grants from Merck and Seagen.
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Please take a few minutes to participate in the optional pre-test. It will help us measure the knowledge gained by participating in this activity.