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CME: Osteoporosis in men: An underappreciated and under-treated condition


Activity Description / Statement of Need:

In this online, self-learning activity:

Osteoporosis is characterized by low bone mass and deterioration of bone tissues, which leads to an increased risk of skeletal fractures. Although osteoporosis is generally considered as a women’s health issue and often overlooked problem in men, osteoporosis in men is also an important public health issue, and its prevalence is increasing as the general population ages – rising to 11% in men by age 80. Around 1-2 million men in the United States have been estimated to have clinical osteoporosis, and an additional 8-13 million men identified to have low bone mass. In sum, 35% of men are considered to have low bone density by age 50, and that number rises to 53% by age 80.

This program has been designed to bring HCPs’ knowledge of the rationale behind prevention and treatment of male osteoporosis up to date and to improve their competence and performance in treating and preventing it.

Target Audience:

The following HCPs: Primary care physicians and endocrinologists; physician assistants, nurse practitioners, and pharmacists who practice in endocrinology and internal medicine; and any other HCPs with an interest in or who clinically encounter male patients with osteoporosis.

Commercial Support Disclosure: This program is supported by an educational grant from Amgen.

This activity is free of charge.

Release Date: August 08, 2021 -- Expiration Date: August 08, 2023

Faculty: Peng Fan, MD


Faculty introduction, disclosures

Introduction content: Review of male osteoporosis

· Epidemiology

  • Natural history of bone loss in men, defining clinical features
  • Causes and risk factors
  • Impact of fracture on patient outcomes
  • Barriers to identification of osteoporosis in men, fracture risk, and whom to screen [Learning objective #1]
  • Diagnosis and the consequences of under-diagnosis [Learning objective #1]

Treatment options

· Consideration of underlying conditions and related treatment

· Non-pharmacologic, nutritional, and over-the-counter recommendations and lifestyle modifications

· Who should receive therapy (eu- vs. hypogonadal men, androgen-deprivation therapy, etc.)

· Choice of agent, mono- vs. combination therapy [Learning objective #2]

  • Benefits and risks of therapy: the evidence [Learning objective #2]
  • Monitoring response, duration of therapy [Learning objective #2]
  • Individualizing therapy and barriers to effective treatment [Learning objective #2]
  • Investigational therapies

· Patient case(s) [Learning objective #3]

Summary, conclusions, and best practice recap

Learning Objectives

By the end of the session the participant will be able to:

  • Recall the challenges preventing earlier diagnosis of osteoporosis in men and the consequences of under-diagnosis
  • Identify the treatment modalities currently available for management of osteoporosis in men and discuss the evidence supporting them
  • Formulate a treatment plan for a male patient with osteoporosis


ACCME Activity #201759862


Faculty Disclosure and Resolution of COI

As a provider of continuing medical education, it is the policy of ScientiaCME to ensure balance, independence, objectivity, and scientific rigor in all of its educational activities. In accordance with this policy, faculty and educational planners must disclose any significant relationships with commercial interests whose products or devices may be mentioned in faculty presentations, and any relationships with the commercial supporter of the activity. The intent of this disclosure is to provide the intended audience with information on which they can make their own judgments. Additionally, in the event a conflict of interest (COI) does exist, it is the policy of ScientiaCME to ensure that the COI is resolved in order to ensure the integrity of the CME activity. For this CME activity, any COI has been resolved thru content review ScientiaCME.

Faculty Disclosure: Peng Thim Fan, MD, FACP, Clinical Professor of Medicine, Division of Rheumatology, David Geffen School of Medicine at UCLA, has received financial compensation for Speakers’ Bureau from Amgen (Prolia, Evenity), Abbvie, Pfizer, Sanofi, Genzyme Regeneron, Radius (Tymlos).

Disclosures of Educational Planners: Charles Turck, PharmD, BCPS, BCCCP, President of ScientiaCME, has no relevant financial disclosures.

All relevant financial relationships have been mitigated.

ScientiaCME adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers or others are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Commercial Support Disclosure: This program is supported by an educational grant from Amgen.


  • Read the learning objectives above
  • Take the Pre-Test (optional). Completion of the pre-test will help us evaluate the knowledge gained by participating in this CME activity.
  • View the online activity. You may view this is in more than one session, and may pause or repeat any portion of the presentation if you need to.
  • Minimum participation threshold: Take the post-test. A score of 70% or higher is required to pass and proceed to the activity evaluation.
  • Complete the activity evaluation and CME registration. A CE certificate will be emailed to you immediately.

Cultural/Linguistic Competence & Health Disparities

System Requirements

Windows 7 or above
Internet Explorer 8
*Adobe Acrobat Reader
Mac OS 10.2.8
Safari or Chrome or Firefox
*Adobe Acrobat Reader
Internet Explorer is not supported on the Macintosh

*Required to view Printable PDF Version

Perform Pre-Test (optional)

Please take a few minutes to participate in the optional pre-test. It will help us measure the knowledge gained by participating in this activity.

Additional Courses That Are Related To This Activity

Identifying and treating people at high risk for fracture from postmenopausal osteoporosis

Optimizing Primary and Secondary Fracture Prevention in Men with Osteoporosis

Postmenopausal osteoporosis risk stratification and treatment of those at high risk for fracture